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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKC
All Species:
27.58
Human Site:
S245
Identified Species:
46.67
UniProt:
Q9UQB9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQB9
NP_001015878.1
309
35591
S245
P
F
E
S
A
S
H
S
E
T
Y
R
R
I
L
Chimpanzee
Pan troglodytes
XP_001142357
309
35587
S245
P
F
E
S
A
S
H
S
E
T
Y
R
R
I
L
Rhesus Macaque
Macaca mulatta
XP_001098364
471
52859
S407
P
F
E
S
T
S
H
S
E
T
Y
R
R
I
L
Dog
Lupus familis
XP_849906
346
39574
N281
P
F
E
S
A
S
H
N
E
T
Y
R
R
I
V
Cat
Felis silvestris
Mouse
Mus musculus
O88445
282
32888
S218
P
F
E
S
S
T
S
S
E
T
Y
R
R
I
R
Rat
Rattus norvegicus
O55099
343
39216
S282
P
F
E
S
P
S
H
S
E
T
Y
R
R
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
Q234
P
F
E
A
E
T
Y
Q
E
T
Y
R
S
I
S
Chicken
Gallus gallus
XP_425725
409
46456
Q349
P
F
E
A
Q
T
Y
Q
E
T
Y
R
A
I
S
Frog
Xenopus laevis
Q6GPL3
368
41997
S302
P
F
D
S
P
S
H
S
E
T
H
R
R
I
V
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
A255
P
F
E
T
A
S
H
A
E
T
Y
K
R
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
E257
P
F
E
S
N
S
T
E
S
T
Y
S
K
I
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
S232
P
F
E
H
E
D
Q
S
K
T
Y
A
A
I
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q683C9
282
32738
S220
P
F
E
A
R
E
H
S
E
T
Y
K
R
I
V
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
D307
P
F
E
E
E
M
K
D
T
T
Y
K
R
I
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
63.4
70.5
N.A.
72.4
67.3
N.A.
64.7
52.3
58.1
65.3
N.A.
43.1
N.A.
54.6
N.A.
Protein Similarity:
100
100
64.7
78.9
N.A.
82.5
79.3
N.A.
78.3
62.3
71.1
78.7
N.A.
62.6
N.A.
68.9
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
73.3
86.6
N.A.
53.3
53.3
73.3
73.3
N.A.
53.3
N.A.
46.6
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
86.6
93.3
N.A.
73.3
73.3
93.3
93.3
N.A.
60
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.3
38.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.8
55.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
22
29
0
0
8
0
0
0
8
15
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
93
8
22
8
0
8
79
0
0
0
0
0
0
% E
% Phe:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
58
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% I
% Lys:
0
0
0
0
0
0
8
0
8
0
0
22
8
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
22
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
100
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
8
15
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
65
72
0
15
% R
% Ser:
0
0
0
58
8
58
8
58
8
0
0
8
8
0
15
% S
% Thr:
0
0
0
8
8
22
8
0
8
100
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
15
0
0
0
93
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _